J. H. Edwards (auth.), Harry Harris, Kurt Hirschhorn (eds.)'s Advances in Human Genetics 1 PDF

By J. H. Edwards (auth.), Harry Harris, Kurt Hirschhorn (eds.)

ISBN-10: 1468409581

ISBN-13: 9781468409581

ISBN-10: 1468409603

ISBN-13: 9781468409604

During the previous few years the technological know-how of human genetics has been increasing virtually explosively. unique papers facing diverse facets of the topic are showing at an more and more fast fee in a really wide variety of journals, and it turns into progressively more tricky for the geneticist and nearly most unlikely for the non geneticist to maintain tune of the enhance­ ments. additionally, new observations and discoveries proper to an total knowing of the topic outcome from investigations utilizing very assorted recommendations and methodologies and originating in numerous various disciplines. hence, investigations in such a number of fields as enzymology, immunology, protein chemistry, cytology, pediatrics, neurology, inner medication, anthropology, and mathematical and statistical genetics, to call yet a number of, have every one contributed effects and concepts of common value to the examine of human genetics. now not unusually it is usually tough for employees in a single department of the topic to evaluate and assimilate findings made in one other. this is a critical proscribing issue at the price of development. hence, there seems to be a true desire for serious overview articles which summarize the positions reached in numerous parts, and it really is was hoping that "Advances in Human Genetics" can help to fulfill this requirement. all the members has been requested to put in writing an account of the location that has been reached within the investigations of a selected subject in a single of the branches of human genetics.

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18. , Co-relations and their measurement, chiefly from anthropometric data, Proc. Roy. Soc. XLV:135 (1888). 19. Haldane, J. B. , The estimation of the frequencies of recessive conditions in man, Ann. Hum. Genet. 8:255-262 (1938). 20. , Quantitative genetics of finger-print patterns, Brit. Med. Bull. 17:247250 (1961). 21. Karn, M. , and L. S. Penrose, Birthweight and gestation time in relation to maternal age, parity and infant survival, Ann. Hum. Genet. 16:147-164 (1951). 22. , and K. Pearson, On the laws of inheritance in man.

Supplementary tables for finding the correlation coefficient from tetrachoric groupings, Biometrika VIII:385 (1914). 13. Falconer, D. , "An Introduction to Quantitive Genetics," Oliver & Boyd, London (1960). 14. Falconer, D. , The inheritance of liability to certain diseases, estimated from the incidence among relatives, Ann. Hum. Genet. 29:51 (1965). 15. Falconer, D. , The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus, Ann. Hum.

226 DuPraw 71 has pointed out that autoradiographic analysis can be misleading under conditions where only relatively heavily labeled segments reach optimal grain densities. His folded-fiber model of the chromosome shows clearly how the presence of label can easily go undetected at certain levels along a chromatid, and provides an explanation of Stubblefield's observation 264 that regions of high labeling intensity are often connected by intermediate areas of lower specific activity. DNA SYNTHESIS AND THE CELL CYCLE The Timing of DNA Synthesis The Cell Cycle and the S Period of DNA Synthesis When somatic cells are exposed to a labeled precursor of DNA for a short time, say, 10 min, only a proportion of the interphase cells, and none of 44 Orlando J.

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Advances in Human Genetics 1 by J. H. Edwards (auth.), Harry Harris, Kurt Hirschhorn (eds.)

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