Bioprocess Engineering Principles, Second Edition by Pauline M. Doran Ph.D. PDF

By Pauline M. Doran Ph.D.

ISBN-10: 012220851X

ISBN-13: 9780122208515

This welcome re-creation covers bioprocess engineering rules for the reader with a constrained engineering history. It explains method research from an engineering perspective, utilizing labored examples and difficulties that relate to organic platforms. program of engineering thoughts is illustrated in components of contemporary biotechnology corresponding to recombinant protein creation, bioremediation, biofuels, drug improvement, and tissue engineering, in addition to microbial fermentation. the most sub-disciplines in the engineering curriculum are all coated; fabric and effort Balances, shipping procedures, Reactions and Reactor Engineering. With new and extended fabric, Doran's textbook is still the booklet of selection for college kids trying to circulate into bioprocess engineering.

NEW TO THIS EDITION:

  • All chapters completely revised for present advancements, with over two hundred pgs of recent fabric, together with major new content material in:
    • Metabolic Engineering
    • Sustainable Bioprocessing
    • Membrane Filtration
    • Turbulence and Impeller Design
    • Downstream Processing
    • Oxygen move Systems
  • Over one hundred fifty new difficulties and labored examples
  • More than a hundred new illustrations

New to this edition:

  • All chapters completely revised for present advancements, with over two hundred pgs of recent fabric, together with major new content material in:
    • Metabolic Engineering
    • Sustainable Bioprocessing
    • Membrane Filtration
    • Turbulence and Impeller Design
    • Downstream Processing
    • Oxygen move Systems
  • Over a hundred and fifty new difficulties and labored examples
  • More than a hundred new illustrations

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Extra info for Bioprocess Engineering Principles, Second Edition

Example text

4 C represents the actual temperature range by which the reading is uncertain, it is known as the absolute error. 7%. Because most values of uncertainty must be estimated rather than measured, there is a rule of thumb that magnitudes of errors should be given with only one or sometimes two significant figures. A flow rate may be expressed as 146 6 10 gmol h21, even though this means that two, the 4 and the 6, in the result are uncertain. The number of digits used to express the result should be compatible with the magnitude of its estimated error.

4 Types of Error There are two broad classes of measurement error: systematic and random. A systematic error is one that affects all measurements of the same variable in the same way. If the cause of systematic error is identified, it can be accounted for using a correction factor. For example, errors caused by an imperfectly calibrated analytical balance may be identified using standard weights; measurements with the balance can then be corrected to compensate for the error. Systematic errors easily go undetected; performing the same measurement using different instruments, methods, and observers is required to detect systematic error.

There is a 68% chance that the true population mean X falls within the interval x 6 σm , and about a 95% chance that it falls within the interval x 6 2σm . The range 62σm is therefore sometimes called the 95% confidence limit for the mean. Clearly, the smaller the value of σm, the more confidence we can have that the calculated mean x is close to the true mean X. Therefore, to report the results of repeated measurements, we usually quote the calculated sample mean as the best estimate of the variable, and the standard error as a measure of the confidence we place in the result.

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Bioprocess Engineering Principles, Second Edition by Pauline M. Doran Ph.D.


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