By John Villadsen, Jens Nielsen, Gunnar Lidén
Integrating fresh learn at the body structure and modelling of bioreactions and bioreactors, the authors current a complete, unified advent to the rules and practices of the sphere. The paintings positive factors approximately a hundred precise layout examples and difficulties, a lot of that are compatible for hands-on demonstrations on a private laptop or for increased study. The textual content will function a hugely instructive consultant for college kids in bioengineering and biotechnology, in addition to biochemical, chemical, and environmental engineering.
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2. Facilitated diffusion A substrate is transported across a (lipid) membrane by a carrier molecule, which is present in the membrane either in free form (concentration e) or bound to the substrate (concentration Sme). The free substrate concentration just inside the membrane at z = 0 is Sma = Kas a, and at the other face of the membrane, at z = d the concentration is 5mb = Kbs b (see Fig. 2). Binding between substrate and carrier is reversible. and the net rate of complex formation is rm . 2) To simplify the discussion we shall assume that Ku = Kh = K.
20) is used, and from these equations the stoichiometric coefficients can be calculated. 3. 9. Summary of elemental matriees and their dimension. : E*p IxN IxM IxN Ix L IxM Extracellular substrates Extracellular metabolie produets Intracellular substrates Biomass eomponents Intracellular metabolie produets E, Ex Ep content of the ith element in the jth reactant is placed in the ith row and the jth column). 9. In many cases E! 1. lethe reactants contain carbon we scale the elemental coefficients with respect to the carbon content, so the elemental coefficient for carbon always becomes 1 or O.
6). , the ATPase mayaiso pump protons out ofthe cells with the expenditure of ATP, and this is also considered to be a primary active transport process. The proton transport is illustrated in Fig. 3. of a previously established gradient of another substance. If the two substances are transported in the same direction, the transport process is called symport; if they are transported in opposite directions, it is ca lIed antiport ; and if an electrochemical potential drives the ftow of ions, it is called uniport (see Fig.
Bioreaction Engineering Principles by John Villadsen, Jens Nielsen, Gunnar Lidén