By Birgit Weyand, Massimo Dominici, Ralf Hass, Roland Jacobs, Cornelia Kasper
Engineered MSCs from Patient-Specific iPS Cells, by means of Irina Eberle, Mohsen Moslem, Reinhard Henschler, Tobias Cantz
Fate of Intravenously Injected Mesenchymal Stem Cells and value for medical program, by means of Beate Wagner, Reinhard Henschler
The Implications of Stem mobilephone purposes for ailments of the breathing approach, by means of Mei Ling Lim, Philipp Jungebluth, Paolo Macchiarini
Potential of Mesenchymal Stem mobilephone functions in Plastic and Reconstructive surgical procedure, by means of Birgit Weyand, Peter M. Vogt
General rules for the Regeneration of Bone and Cartilage, by means of Michael Jagodzinski, C. Haasper
Adult Mesenchymal Stem Cells Explored within the Dental box, by means of ok. M. Fawzy El-Sayed, C. Dörfer, F. Fändrich, F. Gieseler, M. H. Moustafa, H. Ungefroren
Mesenchymal Stem phone treatment and Lung ailments, via Khondoker M. Akram, Sohel Samad, Monica Spiteri, Nicholas R. Forsyth
Mesenchymal Stem Cells as mobile Immunotherapeutics in Allogeneic Hematopoietic Stem cellphone Transplantation, by way of Claudia Papewalis, Daniela Topolar, Barbara Götz, Stefan Schönberger, Dagmar Dilloo
New Cell-Based remedy Paradigm: Induction of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells into Pro-Inflammatory MSC1 and anti inflammatory MSC2 Phenotypes, through Aline M. Betancourt
Interactions among Mesenchymal Stem Cells and Dendritic Cells, by means of Grazia Maria Spaggiari, Lorenzo Moretta
MSC and Tumors: Homing, Differentiation, and Secretion impression healing strength, via Naomi D’souza, Jorge Sans Burns, Giulia Grisendi, Olivia Candini, Elena Veronesi, Serena Piccinno, Edwin M. Horwitz, Paolo Paolucci, Pierfranco Conte, Massimo Dominici
Sources of Mesenchymal Stem Cells: present and destiny medical Use, by means of Michela Pozzobon, Martina Piccoli, Paolo De Coppi
Role of the european Framework in rules of Stem Cell-Based items, through Giovanni Migliaccio, Cristina Pintus
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Additional resources for Mesenchymal Stem Cells - Basics and Clinical Application II
71. 72. 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84. 37 integrity through regulation of endogenous epithelial cell homeostasis. Cell Death Differ 17(6):952–961 (Epub 2009 Dec 18) Shi M, Li J, Liao L, Chen B, Li B, Chen L, Jia H, Zhao RC (2007) Regulation of CXCR4 expression in human mesenchymal stem cells by cyto-kine treatment: role in homing efficiency in NOD/SCID mice. Haematologica 92:897–904 Shi C, Jia T, Mendez-Ferrer S, Hohl TM, Serbina NV, Lipuma L, Leiner I, Li MO, Frenette PS, Pamer EG (2011) Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands.
This alteration highly promoted MSC localization into bone tissue. In further work, they suggested that these engineered MSCs mediate their arrest on endothelial cells via capturing E-selectin, followed by ligation of alpha4 beta1 integrin . The ability of human MSCs to adhere reversibly to TNF-alpha pre-stimulated endothelial cells was compared to human CD34 ? hematopoietic progenitor cells or freshly isolated human blood mononuclear cells in a flow chamber model employing integrins alpha4 beta1 and its ligand, vascular cell adhesion molecule (VCAM)-1 .
HMSC engraftment outside the locally irradiated regions was also increased, arguing for both local and systemic effects of irradiation for MSC engraftment. Long-term engraftment was, however, not investigated. Sémont et al.  in an additional study specifically investigated the engraftment, but also the efficacy of MSCs in a model of radiation-induced gastrointestinal tract failure. They demonstrated accelerated recovery in the group receiving hMSC in immunodeficient mice, with decreased apoptosis of epithelial cells and increased proliferation within the small intestinal mucosa.
Mesenchymal Stem Cells - Basics and Clinical Application II by Birgit Weyand, Massimo Dominici, Ralf Hass, Roland Jacobs, Cornelia Kasper