By A Wallace Hayes
Now in its fourth variation, this middle textual content and traditional reference in toxicology has once more been up-to-date to include the newest checking out approaches and tackle new demanding situations confronted via toxicologists. the writer brings jointly greater than 70 individual investigators to element present checking out tactics, provide directions on facts interpretation and spotlight significant parts of controversy. The booklet bargains with the tools of toxicology, in addition to rules and brokers. New chapters on publicity review and epidemiology for toxicologists were additional. The reader will locate an in-depth examine the foundations underlying toxicology, comparable to absorption, distribution, metabolism and excretion, in addition to issues facing pharmacokinetics. ideas and techniques of Toxicology, Fourth variation permits the operating toxicologist, no matter if a senior expert or graduate scholar, to appreciate and use uncomplicated experiments in toxicology.
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Additional resources for Principles and Methods of Toxicology: 4th Edition
He advocated the doctrine of signatures, which stated that the therapeutic usefulness of a plant, mineral, or animal was based on its resemblance to the signs of a disease. This doctrine persisted for many centuries and still has a few proponents. , chalk in flour, herbs, and spices). ” His contributions to toxicology include lists of poisons and their biological effects and his questioning of the value of nonspecific antidotes like mithridatics. Arab The Arabs made significant contributions to the health professions.
Shen Nung wrote a 40-volume herbal entitled Pen Ts’ao or Pun Tsao (the Great Herbal or Chinese Materia Medica) around 2735 BC. It contained lists of poisonous plants, plants with medicinal value (365), and drugs (265, 240 of which are vegetable in origin). The effects of plants and drugs and appropriate antidotes were described. Included among the drugs were iodine, aconite (also used as an arrow poison), opium, cannabis, rhubarb, alum, camphor, iron, sulfur, and mercury. He was also reputed to have discovered a number of drugs and experimented upon himself.
The section on drugs listed 760 indigenous medicinal plants, of which many were used externally as ointments, baths, sneezing powders, inhalations; it also listed animal and mineral remedies. The fifth section, the Kalpa Sthana, was the section on toxicology and contained mostly antidotes. ). Other topics discussed included malaria and the role of the mosquito and plague and the influence of rats. Greek There are many Greek legends and myths involving gods and goddesses concerned with poisons and poisoning.
Principles and Methods of Toxicology: 4th Edition by A Wallace Hayes