George T. J. Huang, Irma Thesleff's Stem Cells, Craniofacial Development and Regeneration PDF

By George T. J. Huang, Irma Thesleff

ISBN-10: 1118279239

ISBN-13: 9781118279236

Stem Cells, Craniofacial improvement and Regeneration is an creation to stem cells with an emphasis on their function in craniofacial improvement. Divided into 5 sections, chapters construct from simple introductory details at the definition and features of stem cells to more indepth explorations in their position in craniofacial improvement. part I covers embryonic and grownup stem cells with a spotlight at the craniofacial quarter, whereas sections II-IV disguise the improvement and regeneration of craniofacial bone, the teeth, temporomandibular joint, salivary glands and muscle. Concluding chapters describe the present, state-of-the-art learn using stem cells for craniofacial tissue bioengineering to regard misplaced or broken tissue.
The authoritative source for dentistry scholars in addition to craniofacial researchers on the graduate and post-graduate point, Stem Cells, Craniofacial improvement and Regeneration explores the swiftly increasing box of stem cells and regeneration from the point of view of the dentistry and craniofacial group, and issues the best way ahead in components of tissue bioengineering and craniofacial stem telephone therapies.

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Extra info for Stem Cells, Craniofacial Development and Regeneration

Sample text

2A). Proper migration of the neural crest is essential to form a functional PNS, and tissue microenvironments play critical roles in dynamically regulating neural crest cell migration. , 2008), and a common feature of chick trigeminal and epibranchial ganglia is the expression of N-cadherin and Robo2 on placodal neurons and Slit1 on neural crest cells (Shiau and Bronner-Fraser, 2009). N-cadherin localizes to intercellular adherens junctions between placodal neurons during ganglion assembly, and depletion of N-cadherin causes loss of proper ganglion coalescence, similar to that observed after loss of Robo2, suggesting that the two pathways might intersect.

2003). , 2003). Although much is known about the function of VEGF signaling during vascular development, the role of VEGF signaling in patterning and morphogenesis of the peripheral nervous system during early embryogenesis has not yet been thoroughly explored. Furthermore, it is not known whether endothelial cells and the vascular network influences neural crest development or whether VEGF signaling plays a critical role in patterning neural crest cell formation, migration, and/or differentiation.

2003). VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol 161(6):1163–1177. Gorlin RJ, Cohen MM, Levin LS (1990). Syndromes of the Head and Neck , Oxford University Press, Oxford, UK. Grammatopoulos GA, Bell E, Toole L, Lumsden A, Tucker AS (2000). Homeotic transformation of branchial arch identity after Hoxa2 overexpression. Development 127(24):5355–5365. Hall BK (1999). The Neural Crest in Development and Evolution, Springer-Verlag, New York. Harland R (2000).

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Stem Cells, Craniofacial Development and Regeneration by George T. J. Huang, Irma Thesleff


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